Parkinson 's Disease And The Disease

Parkinson disease (PD) is one of the most common neurologic disorders. and it affects approximately 1% of individuals older than 60 years old. Parkinson’s disease is a condition that progresses slowly by treatment. In addition, loss of pigmented dopaminergic neurons of the substantianigra pars compacta and the presence of Lewy bodies and Lewyneurites are the two major neuropathologic findings in Parkinson disease (Hauser, 2016).

By the time someone shows signs and symptoms of Parkinson 's, Dopamine production in the brain has been reduced by 60 to 80% and is fairly advanced. This results in the most recognizable sign of Parkinson 's disease, the resting tremor of the hand or hands. During deliberate movement, the resting tremor goes away, at first. At rest, the tremor will become exacerbated,

The main symptoms and signs of Parkinson’s are bradykinesia, rigidity and rest tremor. Parkinson’s is mainly seen as a movement disorder, but other areas of health problems are associated with it. These include depression and dementia along with autonomic disturbances and pain, although considered to be rare they can present at a later stage of the condition. These rarer symptoms, as they progress, can lead to substantial disability and handicap which harms quality of life for the person living with Parkinson’s, this also has an impact on families and carer’s.

Parkinson disease (PD), also referred to as Parkinson’s disease and paralysis agitans, is a progressive neurodegenerative disease that is the third most common neurologic disorder of older adults. It is a debilitating disease affecting motor ability and is characterized by four cardinal symptoms: tremor rigidity, bradykinesia or kinesis (slow movement/no movement), and postural instability. Most people have primary, or idiopathic, disease. A few patients have secondary parkinsonian symptoms from conditions such as brain tumors and certain anti-psychotic drugs.

Parkinson’s is a progressive neurodegenerative disease, primarily affecting voluntary, precise, and controlled movement. Parkinson’s occurs when cells in a part of the brain called the substantia nigra die off. These cells are responsible for producing dopamine. With less and less dopamine, a person has less and less ability to regulate their movements, body and emotions. The terms "familial Parkinson's disease" and "sporadic Parkinson's disease" are used to differentiate genetic from truly idiopathic forms of the disease.

Parkinson’s disease is a disorder that progresses over time. It affects your movement through your nervous system; the disorder causes stiffness, and slow movement in your body. Most noticeably started in little “tremors” in your hands it gradually increases over time. Early stages consists little expression in your face or no movement in your arms as you walk. Your speech may also slur, or slow down. Symptoms usually worsen over time.

Parkinson Disease (PD) is a neurodegenerative disease symptomized by tremor, muscular rigidity, and slow imprecise movements. Typically, the disease affects middle-aged and elderly individuals. PD is associated with degeneration of the basal ganglia of the brain causing a deficiency of the neurotransmission of dopamine.

Parkinson's Disease affects the way the body moves, in the brain, there's an important chemical called Dopamine which controls movements that the body makes and sends signals to the brain to tell the body where to move. Having Parkinson's Disease, the nerve cells in the brain break down to where there isn't enough dopamine and have trouble controlling movements . Figure 1, shows a before and after picture of where in the brain the nerve cells which contain dopamine are located and how the nerve cells become damaged when a person has Parkinson's.

Parkinson’s Disease is known as one of the most common progressive and chronic neurodegenerative disorders. It belongs to a group of conditions known as movement disorders. Parkinson disease is a component of hypokinetic disorder because it causes a decreased in bodily movement. It affects people who are usually over the age of 50. It can impair an individual motor as well as non-motor function. Some of the primary symptoms of Parkinson’s disease are characterized by tremors or trembling in hands, legs and arms. In early symptoms the tremor can be unilateral, appearing in one side of body but progression in the disease can cause it to spread to both sides; rigidity or a resistant to movement affects most people with Parkinson’s disease,

Parkinson’s disease is a disorder that affects the brain, which then affects multiple other processes in the body. The disease is known to progress slowly and many patients are diagnosed when they are around 60, but early onset is a possibility. Parkinson’s is a “neurodegenerative” disease, meaning, the nervous system deteriorates, particularly brain cells called neurons. Parkinson’s is second to alzheimer’s in terms of being the most common neurodegenerative disease. There are over 500,000 affected by Parkinson’s.  The disease deteriorates brain cells that produce dopamine. Dopamine is a chemical found in the brain that helps control movements and emotions. With the lower amount of dopamine, patients tend to have less emotion and movements.

Definition: “Parkinson’s disease is a chronic, progressive disease of the nervous system characterized by the cardinal features of rigidity, bradykinesia, tremor, and postural instability” (O’Sullivan and Schmitz, 2007). The condition can develop between age group 60 and 80 years and symptoms mostly appear around 60 years of age (O’Sullivan and Schmitz, 2007).

Parkinson’s Disease is a very common disorder these days. Over 10 million people live daily with Parkinson worldwide. Parkinson’s Disease was named after an English surgeon James Parkinson who wrote a detailed description essay called Shaking Palsy in 1817. The average age for Parkinson’s Disease is between 45 to 70 years old but you can also have juvenile or young onset as well. Most common symptoms of Parkinson are tremors, bradykinesia or akinesia, or rigidity or stiffness, and balance disorder. Parkinson’s Disease doesn’t have a cure and the cause is unknown it could be a number of things genetics, environmental triggers, age, or gender. Parkinson’s Disease happens because the dopaminergic neuron dies and

Parkinson disease (PD) is a condition consisting of many unanswered questions. What causes it? Is it a genetic disorder? How will an individual know if they will be diagnosed with it in their lifetime? The list of enquiries one might present is endless. However, before even attempting to answer any questions, it is essential to understand the disease as a whole. In order to do so, grasping basic background information as well as data on PD is necessary. Following that, discussing material regarding the science behind the disease will provide a deeper understanding when examining the subsequent etiologies, signs, and symptoms.

There are many symptoms when it comes to having Parkinson’s disease. The first of the types are motor symptoms. The most common, but major symptom of PD is dyskinesias or tremors. Tremors is when you have little, uncontrollable movement in you body, such as in your arms, in your legs, and even in your face. Also medicines such as MAO-B inhibitors, COMT inhibitors, and others can cause dyskinesias to get worse and put you in a not so good position. (Lazarus Motor)

Parkinson disease (PD) is a progressive neurodegenerative disorder characterized mainly by physical and psychological disabilities. This disorder was named after James Parkinson, an English physician who first described it as shaking palsy in 1817 (Goetz, Factr, and Weiner, 2002). Jean- Martin Charcot, who was a French neurologist, then progressed and further refined the description of the disease and identified other clinical features of PD (Goetz, Factr, and Weiner, 2002). PD involves the loss of cells that produce the neurotransmitter dopamine in a part of the brain stem called the substansia nigra, which results in several signs and symptoms (Byrd, Marks, and Starr, 2000). It is manifested clinically by tremor,